Wiley, British Journal of Dermatology, 2(172), p. 534-536, 2014
DOI: 10.1111/bjd.13271
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Psoriasis is currently considered a systemic inflammatory disorder associated with several comorbidities and increased risk of cardiovascular disease (CVD)1. Several proinflammatory cytokines are overexpressed cutaneous and systemically and may be responsible for skin lesions but also for psoriasis-associated conditions1. Epicardial adipose tissue (EAT), a type of visceral fat surrounding the heart, is now regarded as an important factor in the pathogenesis of coronary atherosclerosis and CVD, through inflammatory burden proximal to the coronary arteries, and has been shown to be increased in psoriasis patients independently of abdominal visceral fat (AVF) and to be associated with subclinical atherosclerosis2.This article is protected by copyright. All rights reserved.