Human glucose-6-phosphate dehydrogenase gene carried on a yeast artificial chromosome encodes active enzyme in monkey cells
Journal article published in 1990 by
Michele D'Urso,
Ileana Zucchi,
Alfredo Ciccodicola,
Giuseppe Palmieri 
,
Fatima E. Abidi,
David Schlessinger
,
Fatima E. Abidi,
David Schlessinger
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Abstract
Yeast artificial chromosomes (YACs) permit the cloning of large tracts of human DNA. A YAC containing the human glucose-6-phosphate dehydrogenase gene is shown to encode active enzyme, supporting the inference that the YAC conserves the structure of the genomic DNA.