Attenuation laws in acceleration and displacement for Mexican subduction earthquakes are presented. The obtained attenuation laws are the result of the analysis of a seismic database of more than 200 earthquakes registered since 1966 in the subduction zone of the Mexican Pacific Coast, the most active seismic zone in the country. Approximately 4000 pairs of accelerograms in each one of the horizontal components were analyzed one by one to define the final database. These attenuation laws are needed to improve the design spectra of the proposed Mexican guidelines for base-isolated structures, as these relationships are the required first step to define later uniform hazard spectra for displacements (isolation system) and accelerations (structure above the isolation system).