Published in
Wiley, Angewandte Chemie International Edition, 42(51), p. 10523-10527, 2012
Wiley, Angewandte Chemie, 42(124), p. 10675-10679, 2012
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Conjugation of Transferrin to Azide-Modified CdSe/ZnS Core-Shell Quantum Dots using Cyclooctyne Click Chemistry
Journal article published in 2012 by
Christine Schieber,
Alessandra Bestetti,
Jet Phey Lim,
Anneke D. Ryan,
Tich-Lam Nguyen,
Robert Eldridge,
Anthony R. White 
,
Paul A. Gleeson,
Paul S. Donnelly,
Spencer J. Williams ,
Paul Mulvaney
,
Paul A. Gleeson,
Paul S. Donnelly,
Spencer J. Williams ,
Paul Mulvaney
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Abstract
Twinkle twinkle quantum dot: Conjugation of biomolecules to azide-modified quantum dots (QDs) through a bifunctional linker, using strain-promoted azide-alkyne cycloaddition with the QD and a squaramide linkage to the biomolecule. Transferrin-conjugated QDs were internalized by transferrin-receptor expressing HeLa cells.