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Wiley, Rapid Communications in Mass Spectrometry, 11(25), p. 1609-1616

DOI: 10.1002/rcm.5002

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Two‐dimensional Fourier transform ion cyclotron resonance mass spectrometry: reduction of scintillation noise using Cadzow data processing

Journal article published in 2011 by Maria A. van Agthoven ORCID, Marie‐Aude Coutouly, Christian Rolando, Marc‐André Delsuc
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

In two-dimensional Fourier transform ion cyclotron resonance mass spectrometry (2D FTICR-MS), scintillation noise, caused mostly by fluctuations in the number of ions in the ICR cell, is the leading cause for errors in spectrum interpretation. In this study, we adapted an algorithm based on singular value decomposition and first introduced by Cadzow et al. (IEE Proceedings Pt. F 1987, 134, 69) to 2D FTICR-MS and we measured its performance in terms of noise reduction without losing signal information in the 2D mass spectrum.