Elsevier, Tetrahedron Letters, 17(35), p. 2691-2694
DOI: 10.1016/s0040-4039(00)77007-9
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A cytotoxic alkaloid, lepadiformine 1, with a new heterocyclic skeleton, has been isolated from the ascidian Clavelina lepadiformis. The structure of 1 was established on the basis of chemical properties and by spectroscopic means : it includes a unique zwitterionic-like moiety.