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Polskie Towarzystwo Biochemiczne, Acta Biochimica Polonica, 4(48), p. 1143-1146, 2001

DOI: 10.18388/abp.2001_3880

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Synthesis and application of chiral triazine condensing reagents prepared from esters of amino acids

Journal article published in 2001 by Z. J. Kamiński ORCID, Kamiński Zj, Zajac Kj, K. J. Zajac, K. Jastrzabek
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Treatment of cyanuric chloride with chiral amines or esters of chiral amino acids gave chiral 2,4-dichloro-6-alkylamino-1,3,5-triazines (2-5) in 49-69% yield, which were found useful as coupling reagents. Enantioselective activation and enantioselective aminolysis in the presence of 2-5 was observed.