Natural radioactivity measurements represent an interesting tool to study geodynamical events or soil geophysical characteristics. In this direction we carried out, in the last years, several radionuclide monitoring both in the volcanic and tectonic areas of the oriental Sicily. In particular we report in-soil Radon investigations, in a tectonic area, including both laboratory and in-site measurements, applying three different methodologies, based on both active and passive detection systems. The active detection devices consisted of solid-state silicon detectors equipped in portable systems for short-time measurements and for long-time monitoring. The passive technique consisted of solid-state nuclear track detectors (SSNTD), CR-39 type, and allowed integrated measurements. The performances of the three methodologies were compared according to different kinds of monitoring. In general the results obtained with the three methodologies seem in agreement with each other and reflect the tectonic settings of the investigated area.