The impacts of El Niño and La Niña on the rainfall over southern China in winter half year (November–April) are investigated diagnostically. It is found that positive rainfall anomalies with statistical significance appear over southern China in El Niño winter but no reversed significant rainfall anomalies in La Niña winter. The asymmetry of the rainfall anomalies are related with the asymmetry in anomalous circulation over western North Pacific (WNP) in lower troposphere, with a strong anomalous anticyclone in El Niño winter but a weak anomalous cyclone in La Niña winter. It is revealed that the asymmetric responses in anomalous circulation to El Nino and La Niña are affected by the intraseasonal oscillation (ISO). In El Niño winter the interannual variation is dominant and the ISO is weak, and the strong interannual variation leads to a strong response of the anomalous anticyclone over WNP in winter half year. However, in La Niña winter the ISO is dominant and the interannual variation is weak, and the weak interannual variation results in a weak response of the anomalous cyclone over WNP.