This article presents a sufficient comparison of two types of advanced non-parametric classifiers implemented in remote sensing for land cover classification. A SPOT-5 HRG image of Yanqing County, Beijing, China, was used, in which agriculture and forest dominate land use. Artificial neural networks (ANNs), including the adaptive backpropagation (ABP) algorithm, Levenberg–Marquardt (LM) algorithm, Quasi-Newton (QN) algorithm and radial basis function (RBF) were carefully tested. The LM–ANN and RBF–ANN, which outperform the other two, were selected to make a detailed comparison with support vector machines (SVMs). The experiments show that those well-trained ANNs and SVMs have no significant difference in classification accuracy, but the SVM usually performs slightly better. Analysis of the effect of the training set size highlights that the SVM classifier has great tolerance on a small training set and avoids the problem of insufficient training of ANN classifiers. The testing also illustrates that the ANNs and SVMs can vary greatly with regard to training time. The LM–ANN can converge very quickly but not in a stable manner. By contrast, the training of RBF–ANN and SVM classifiers is fast and can be repeatable.