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Springer, Netherlands Heart Journal, 11(22), p. 493-500, 2014

DOI: 10.1007/s12471-014-0604-2

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Multimodality infarct identification for optimal image-guided intramyocardial cell injections

Journal article published in 2014 by F. J. van Slochteren, R. van Es, S. Koudstaal, T. I. G. van der Spoel, J. P. G. Sluijter, J. Verbree, R. H. R. Pruim, J. P. W. Pluim, T. Leiner, P. A. Doevendans, S. A. J. Chamuleau ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Intramyocardial cell injections in the context of cardiac regenerative therapy can currently be performed using electromechanical mapping (EMM) provided by the NOGA®XP catheter injection system. The gold standard technique to determine infarct size and location, however, is late gadolinium enhanced magnetic resonance imaging (LGE-MRI). In this article we describe a practical and accurate technique to co-register LGE-MRI and NOGA®XP datasets during the injection procedures to ultimately perform image-guided injections to the border zone of the infarct determined by LGE-MRI.