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Medknow Publications, Asian Journal of Transfusion Science, 2(8), p. 139

DOI: 10.4103/0973-6247.137458

Korean J Hematol, 4(47), p. 298

DOI: 10.5045/kjh.2012.47.4.298

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Complications following an unnecessary peri-operative plasma transfusion and literature review

Journal article published in 2012 by Js Raval ORCID, Jh Waters, Dj Triulzi, Mh Yazer
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Plasma is used to correct coagulopathies, but not all coagulation abnormalities are clinically significant enough to require correction before an invasive procedure. We report an 82-year-old female who, in response to a mildly prolonged INR of unknown etiology, was unnecessarily transfused with plasma in advance of elective surgery. The patient suffered a moderately severe transfusion reaction, including hives and voice hoarseness, which caused a 4-week delay in her surgery. This delay and adverse reaction could have been avoided had the principles of evidence based plasma therapy, which we herein review, been followed and if the etiology of the mildly elevated INR been investigated before the day of her surgery.