Pubished version of an article in the journal: Abstract and Applied Analysis. Also available from the publisher at: http://dx.doi.org/10.1155/2013/120543 Open access ; This paper is concerned with the design problem of robust H∞ switching rule for Boost converters with uncertain parameters and disturbances. Firstly, the Boost converter is modeled as a switched affine linear system with uncertain parameters and disturbances. Then, using common Lyapunov function approach and linear matrix inequality (LMI) technique, a novel switching rule is proposed such that the H∞ model reference tracking performance is satisfied. Finally, a simulation result is provided to show the validity of the proposed method.