Objective: To investigate the effect of using noninvasive mechanical ventilation (NIMV) on the respiratory and hemodynamic parameters in acute respiratory failure developed during early postoperative period in chronic obstructive pulmonary disease (COPD) patients who underwent heart surgery. Material and Methods: Forty (40) COPD patients, ivho underivent heart surgery and developed acute respiratory failure following extubation, were included in the study. Patients without spontaneous respiration, who had myocardial infarction, arrhythmia, hypotension or developed shock, uncooperative patients, cases with intense airway secretions and facial deformities were excluded from the study. NIMV was applied with oronasal mask at pressure pressure support ventilator settings of 5 cm H2O PEEP, and 15 cm H2O for patients with respiratory rate >24/min and/or in artery blood PaCO2 >50 mmHg, pH<7.30, PaO2 < 60 mmHg or PaO2/FiO2<250 patients PaCO2 < 45 mmHg and PaO2/FiO2>300 were targeted. Results: Mean arterial pressure (MAP), heart rate, respiratory rate, PaCO2, PaO2, pH results of the patients recorded 1 and 2 hours after the NIMV application were changed statistically significantly when compared with pre-NIMV period (p<0.05). PaO2 was higher and PaCO2, while heart rate, pH and MAP were found to be lower relative to pre-NIMV values. Conclusion: Appropriate use of NIMV improves the patient's respiratory and cardiac parameters In COPD patients who underwent heart surgery and developed respiratory failure after extubation. This can shorten the duration of the intensive care unit and hospital stay of the patients . by preventing repetitive intubations and complications of mechanical ventilation.