Published in
Oxford University Press, Clinical Infectious Diseases, 3(60), p. 432-437, 2014
DOI: 10.1093/cid/ciu795
Links
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- Oxford University Press
- ORCID
- [www.ncbi.nlm.nih.gov] | PDF
- [cid.oxfordjournals.org] | PDF
- [serval.unil.ch] | PDF
- [europepmc.org] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [serval.unil.ch] | PDF
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Combined Use of Mycobacterium tuberculosis-Specific CD4 and CD8 T-Cell Responses Is a Powerful Diagnostic Tool of Active Tuberculosis
Journal article published in 2014 by
Virginie Rozot,
Amelio Patrizia,
Selena Vigano,
Jesica Mazza-Stalder,
Elita Idrizi,
Cheryl L. Day,
Matthieu Perreau,
Catherine Lazor-Blanchet,
Khalid Ohmiti,
Delia Goletti 
,
Pierre-Alexandre Bart,
Willem Hanekom,
Thomas J. Scriba,
Laurent Nicod,
Giuseppe Pantaleo
and other authors.
,
Pierre-Alexandre Bart,
Willem Hanekom,
Thomas J. Scriba,
Laurent Nicod,
Giuseppe Pantaleo
and other authors.
This paper is available in a repository.
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Abstract
Immune-based assays are promising tools to help to formulate diagnosis of active tuberculosis. A multiparameter flow cytometry assay assessing T-cell responses specific to Mycobacterium tuberculosis and the combination of both CD4 and CD8 T-cell responses accurately discriminated between active tuberculosis and latent infection.