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BioMed Central, BMC Genetics, 1(15), 2014

DOI: 10.1186/s12863-014-0100-0

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Identification of genomic regions associated with feed efficiency in Nelore cattle

Journal article published in 2014 by Priscila Sn de Oliveira, Aline Sm Cesar ORCID, Michele L. do Nascimento, Amália S. Chaves, Polyana C. Tizioto, Rymer R. Tullio, Dante Pd Lanna, Antonio N. Rosa, Tad S. Sonstegard, Gerson B. Mourao, James M. Reecy ORCID, Dorian J. Garrick ORCID, Maurício A. Mudadu ORCID, Luiz L. Coutinho, Luciana Ca Regitano
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

BACKGROUND: Feed efficiency is jointly determined by productivity and feed requirements, both of which are economically relevant traits in beef cattle production systems. The objective of this study was to identify genes/QTLs associated with components of feed efficiency in Nelore cattle using Illumina BovineHD BeadChip (770 k SNP) genotypes from 593 Nelore steers. The traits analyzed included: average daily gain (ADG), dry matter intake (DMI), feed-conversion ratio (FCR), feed efficiency (FE), residual feed intake (RFI), maintenance efficiency (ME), efficiency of gain (EG), partial efficiency of growth (PEG) and relative growth rate (RGR). The Bayes B analysis was completed with Gensel software parameterized to fit fewer markers than animals. Genomic windows containing all the SNP loci in each 1 Mb that accounted for more than 1.0% of genetic variance were considered as QTL region. Candidate genes within windows that explained more than 1% of genetic variance were selected by putative function based on DAVID and Gene Ontology.