Published in
Bentham Science Publishers, Mini-Reviews in Medicinal Chemistry, 5(6), p. 603-609
DOI: 10.2174/138955706776876203
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The Therapeutic Potential of Angiotensin-(1-7) as a Novel Renin- Angiotensin System Mediator
Journal article published in 2006 by
Ana Cristina Simões e. Silva 
,
Sérgio Veloso Brant Pinheiro,
Regina Maria Pereira,
Anderson José Ferreira,
Robson Augusto Souza Santos
,
Sérgio Veloso Brant Pinheiro,
Regina Maria Pereira,
Anderson José Ferreira,
Robson Augusto Souza Santos
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Abstract
In this review, we show Angiotensin-(1-7) as a novel Renin Angiotensin System mediator that antagonizes cardiovascular and proliferative effects of Angiotensin II and exerts complex renal actions. We also speculate the possibility of new drugs for the treatment of cardiovascular, genitourinary and hepatic diseases by interfering with ACE2-Angiotensin-(1-7)-Mas axis.