Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial

Sagara, Issaka; Beavogui, Abdoul Habib; Zongo, Issaka; Soulama, Issiaka; Borghini-Fuhrer, Isabelle; Fofana, Bakary; Camara, Daouda; Somé, Anyirékun F.; Coulibaly, Aboubacar S.; Traore, Oumar B.; Dara, Niawanlou; Kabore, Moïse J. T.; Thera, Ismaila; Compaore, Yves D.; Sylla, Malick Minkael; Nikiema, Frederic; Diallo, Mamadou Saliou; Dicko, Alassane; Gil, Jose Pedro; Borrmann, Steffen; Duparc, Stephan; Miller, Robert M.; Doumbo, Ogobara K.; Shin, Jangsik; Bjorkman, Anders; Ouedraogo, Jean-Bosco; Sirima, Sodiomon B.; Djimdé, Abdoulaye A.

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Safety and efficacy of re-treatments with pyronaridine-artesunate in African patients with malaria: a substudy of the WANECAM randomised trial

Journal article published in 2015 by Issaka Sagara, Abdoul Habib Beavogui, Issaka Zongo, Issiaka Soulama

, Isabelle Borghini-Fuhrer, Bakary Fofana, Daouda Camara, Anyirékun F. Somé, Aboubacar S. Coulibaly, Oumar B. Traore, Niawanlou Dara, Moïse J. T. Kabore, Ismaila Thera, Yves D. Compaore, Malick Minkael Sylla and other authors.

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Abstract

Sparse data on the safety of pyronaridine-artesunate after repeated treatment of malaria episodes restrict its clinical use. We therefore compared the safety of pyronaridine-artesunate after treatment of the first episode of malaria versus re-treatment in a substudy analysis.