The near ubiquitously-occurring Bacillus sp. are found to adapt to the antimicrobial activity of nanosilver. Upon prolonged exposure to various levels of nanosilver-stimulated cellular oxidative stress, the bacteria develop stable resistance in the forms of nanosilver tolerance and enhanced extent of growth. As reported by W. Y. Teoh, R. Amal, and co-workers on page 3554, the induced adaptation results in ultimate domination of the nanosilverresistant Bacillus sp. in the microbiota, to which nanosilver is continuously applied.