Highly stable and highly soluble push-pull heptamethine hemicyanines based on the tricyanofuran electron-accepting group can be prepared on a 15 g scale. The compounds display giant second-order nonlinear figure of merit, μβ of up to 31 000×10-48 esu, and lead to a poled material with a second-order nonlinear response, r33 of 90 pm V-1 at 1.06 μm Highly stable and highly soluble push-pull heptamethine hemicyanines based on the tricyanofuran electron-accepting group (see figure) can be prepared on a 15 g scale. The compounds display giant second-order nonlinear figure of merit, μβ of up to 31 000×10-48 esu, and lead to a poled material with a second-order nonlinear response, r33 of 90 pm V -1 at 1.06 μm.