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Taylor and Francis Group, Nucleosides, Nucleotides and Nucleic Acids, 10-12(26), p. 1231-1236

DOI: 10.1080/15257770701528172

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Synthesis and characterization of tetra-end linked oligonucleotides capable of forming monomolecular G-quadruplexes

Journal article published in 2007 by Nicola Borbone, Giorgia Oliviero, Jussara Amato, Stefano D'Errico, Aldo Galeone ORCID, Gennaro Piccialli ORCID, Luciano Mayol ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

The chemical synthesis of two new G-rich Tetra-End-Linked-oligodeoxyribonucleotides (TEL-ODNs) as well as (1)H-NMR and CD spectra of the corresponding monomolecular quadruplexes (IVa and IVb) has been reported. The new TEL-ODNs, characterized by the presence of short branches in the linker moiety, could be very useful for the achievement of monomolecular quadruplexes with predetermined strand orientation.