Published in
Hindawi, Oxidative Medicine and Cellular Longevity, (2016), p. 1-22, 2016
DOI: 10.1155/2016/7361613
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Overview of Alzheimer’s Disease and Some Therapeutic Approaches Targeting Aβby Using Several Synthetic and Herbal Compounds
Journal article published in 2016 by
Sandeep Kumar Singh,
Saurabh Srivastav,
Amarish Kumar Yadav,
Saripella Srikrishna,
George Perry 
This paper is made freely available by the publisher.
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Abstract
Alzheimer’s disease (AD) is a complex age-related neurodegenerative disease. In this review, we carefully detail amyloid-βmetabolism and its role in AD. We also consider the various genetic animal models used to evaluate therapeutics. Finally, we consider the role of synthetic and plant-based compounds in therapeutics.