Cell Press, Chemistry and Biology, 2(21), p. 172-173, 2014
DOI: 10.1016/j.chembiol.2014.02.001
Full text: Unavailable
Prion proteins can be propagated as amyloid fibrils with several different conformational variants. By providing structural information at atomic level for two such variants of a yeast prion, Frederick and colleagues, in this issue of Chemistry & Biology, reveal how conformational flexibility can generate phenotypic diversity.