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Taylor and Francis Group, OncoImmunology, 1(3), p. e27219

DOI: 10.4161/onci.27219

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Early predictive value of multifunctional skin-infiltrating lymphocytes in anticancer immunotherapy

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Bioassays that predict clinical outcome are essential to optimize cellular anticancer immunotherapy. We have recently developed a robust and simple skin test to evaluate the capacity of tumor-specific T cells to migrate, recognize their targets and exert effector functions. This bioassay detects T cells with an elevated antineoplastic potential and hence rapidly identifies patients responding to immunotherapy.