Dissemin is shutting down on January 1st, 2025

Published in

Taylor and Francis Group, Journal of Liposome Research, 2(13), p. 123-130, 2003

DOI: 10.1081/lpr-120020315

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Effect of pH on the Control Release of Microencapsulated Dye in Lecithin Liposomes. II

This paper is available in a repository.
This paper is available in a repository.

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Abstract

The objective of our work has been the microencapsulation of dyes with lecithin from soybean, with the formation of liposomes, as a substitute for synthetic auxiliaries so as to improve the quality of the effluent. Current scenarios promote the disintegration and leakage of the liposomes, such as, changes in temperature, pH, and the use of surfactants. Since dyeing process is a mix of all these parameters, we pretended to study each one separately. Changes in pH at constant temperature induce a release of dye similar with changes in temperature. In acid conditions, we found a very fast initial dye release which doesn't occur in basic conditions. Using carboxyfluorescein, as a pH fluorescence probe, we concluded that the liposome membrane doesn't protect the liposome interior from changes on the external pH.