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MDPI, Materials, 11(5), p. 2292-2305, 2012

DOI: 10.3390/ma5112292

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Cell-Sized Liposomes and Droplets: Real-World Modeling of Living Cells

Journal article published in 2012 by Tsutomu Hamada, Kenichi Yoshikawa ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Recent developments in studies concerning cell-sized vesicles, such as liposomes with a lipid bilayer and water-in-oil droplets covered by a lipid monolayer, aim to realize the real-world modeling of living cells. Compartmentalization with a membrane boundary is essential for the organization of living systems. Due to the relatively large surface/volume ratio in microconfinement, the membrane interface influences phenomena related to biological functions. In this article, we mainly focus on the following subjects: (i) conformational transition of biopolymers in a confined space; (ii) molecular association on the membrane surface; and (iii) remote control of cell-sized membrane morphology.