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Wiley, Advanced Materials, 3(22), p. 352-355, 2010

DOI: 10.1002/adma.200902372

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Controlling the Number of Proteins with Dip-Pen Nanolithography

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Desired numbers of proteins can be positioned on surfaces by using dip-pen nanolithography (DPN). Ferritin nanoarrays are fabricated by direct-writing nanodroplets of a ferritin solution on transmission electron microscopy surfaces. After the contact-angle value of these droplets is determined, the concentration of the inking protein solution and the diameter of the dot-like feature can be modulated to position a single ferritin particle on a surface (see figure).