Published in
American Society of Hematology, Blood, 18(126), p. 2098-2109, 2015
DOI: 10.1182/blood-2015-02-626176
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- [www.ncbi.nlm.nih.gov] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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The forkhead transcription factor FOXP1 represses human plasma cell differentiation
Journal article published in 2015 by
Martine van Keimpema,
Leonie J. Grüneberg,
Michal Mokry 
,
Ruben van Boxtel ,
Menno C. van Zelm,
Paul Coffer,
Steven T. Pals,
Marcel Spaargaren
,
Ruben van Boxtel ,
Menno C. van Zelm,
Paul Coffer,
Steven T. Pals,
Marcel Spaargaren
This paper is made freely available by the publisher.
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Abstract
Key Points Aberrant expression of FOXP1 in human MBCs represses their ability to differentiate into PCs. Human IgG+ MBCs combine lower FOXP1 expression with a higher propensity to differentiate as compared with IgM+ MBCs.