The on-body channel was characterised at various points on the human torso in an anechoic chamber using a pair of wireless sensor modules. The performance of wireless IEEE 802.15.4 sensor nodes operating in the 2.45 GHz ISM frequency band (2.40-2.4835 GHz) is presented over each of the 16 different channels. It is shown that the response at individual carrier frequencies is dependent not only on the initial antenna response, as determined by the on-body measurement in isolation, but also on the overall system performance. Measurement results are also compared with those from the conventional technique using a Vector Network Analyzer.