Running economy (RE) is defined as the energy cost to maintain a sub-maximal running velocity and seems to be affected by individual's neuromuscular characteristics, such as stiffness level. Both resistance training (RT) and whole body vibration training added to RT (WBV + RT) have been shown to influence those characteristics. Thus, it is conceivable that RT and WBV + RT could also affect RE. The objective of this study was to investigate if a 6-week training period of RT and WBV + RT influence RE and vertical stiffness. Fifteen recreational runners were divided into RT or WBV + RT groups. RE, vertical stiffness (VS) and lower-limb maximum dynamic strength (1RM half-squat) were assessed before and after the 6-week training period. There was a main time effect for 1RM, but no other statistically significant difference was observed. Neither conventional RT nor RT performed on a WBV platform improved VS and RE in recreational long distance runners. It is possible that movement velocity was rather low and utilization of stretch-shortening cycle might have been compromised, impairing any expected improvement in RE.