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Portland Press, Biochemical Society Transactions, 6(33), p. 1313-1315, 2005

DOI: 10.1042/bst0331313

Portland Press, Biochemical Society Transactions, 6(33), p. 1313

DOI: 10.1042/bst20051313

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Two functionally distinct pools of Src kinases for PDGF receptor signalling

Journal article published in 2005 by M. Franco ORCID, L. Veracini, A. Boureux, V. Simon, S. Roche, C. Benistant
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The cytoplasmic tyrosine kinases of the Src family (SFK) play important roles in cell responses induced by growth factors, including cell growth, survival and migration. Here, we review how SFK participate in PDGF (platelet-derived growth factor) receptor signalling leading to DNA synthesis and actin assembly. Furthermore, evidence for a spatial compartmentalization of SFK signalling is also discussed.