The effect of magnetization of the spin-polarizing layer (SPL) on the magnetoresistance (MR) is investigated by using different compositions of CoxFe80-xB20 (x = 60, 40, and 20) as spin polarizers in Co/Pd multilayers-based pseudo-spin-valves with perpendicular magnetic anisotropy (PMA). In the case of as-deposited films, the giant magnetoresistance (GMR) was found to decrease with increase of CoFeB thickness from 5 angstrom to 10 angstrom. However, after post-annealing at 250 degrees C, 10 angstrom samples showed a peak of GMR in all compositions. Further increase in annealing temperature causes a reduction in GMR, which was found to be larger in samples with a lower saturation magnetization (M-s). As a function of SPL thickness, the GMR decreases in the case of as-deposited samples. However, post-annealed samples show a larger MR in case of thicker SPL. In the case of thick CoFeB SPL, the magnetization of the soft layer appears to be canted out of the plane. Among the three compositions investigated, the Co60Fe20B20 polarizer shows a stronger PMA due to its lower M-s, leading to the weaker demagnetization. (C) 2012 American Institute of Physics. [doi:10.1063/1.3676424]