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Elsevier, Clinical Microbiology and Infection, 3(12), p. 254-261, 2006

DOI: 10.1111/j.1469-0691.2005.01338.x

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Genetic diversity of Legionella pneumophila inferred from rpoB and dotA sequences

Journal article published in 2006 by K. S. Ko ORCID, H. Miyamoto, H. K. Lee, M.-Y. Park, K. Fukuda, B. J. Park, Y.-H. Kook
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

This study characterised the population structure of Legionella pneumophila by comparing the rpoB (300-bp) and dotA (360-bp) sequences of 267 isolates (18 reference strains, 149 Korean isolates and 100 Japanese isolates). In addition to the six clonal subgroups established previously, four subgroups, P-V to P-VIII, were identified. Subgroupings based on rpoB and dotA sequences were found to correlate with the source of the isolates, and this data may be useful for future epidemiological studies. Fourteen (five Korean and nine Japanese) isolates showed incongruent subgroupings in the rpoB and dotA trees, suggesting that genetic exchange among subgroups, and even among subspecies, may occur frequently in nature.