Comprehensive reviews are given for the major volcanic systems that occur in the greater metropolitan area of Naples, southern Italy; Mt. Somma-Vesuvius to the east and the Campi Flegrei volcanic system to the west. Also included in the review is a detailed discussion of the large, highly explosive Campania Volcanic Zone (CVZ) ignimbrite events. These volcanic areas have been studied for more than 100 years, yet significant differences of opinion exist related to fundamental issues of origin and distribution. We present some alternative views related to petrogenesis on some issues based on more than 25 years of research. The relationship between risk assessment and management that impacts the threatened society or culture and the past and ongoing fundamental volcanological research is an essential part of the science. Countries with limited resources may be forced to accept an increased risk but even highly industrialized societies may not be able to completely eliminate deaths from volcanic eruptions.