The Information Artifact Ontology is an ontology in the domain of information entities. Core to the definition of what it is to be an information entity is the claim that an information entity must be `about' something, which is encoded in an axiom expressing that all information entities are about some entity. This axiom comes into conflict with ontological realism, since many information entities seem to be about non-existing entities, such as hypothetical molecules. We discuss this problem in the context of diagrams of molecules, a kind of information entity pervasively used throughout computational chemistry. We then propose a solution that recognizes that information entities such as diagrams are expressions of diagrammatic languages. In so doing, we not only address the problem of classifying diagrams that seem to be about non-existing entities but also allow a more sophisticated categorisation of information entities. ; Comment: 10 pages, 5 figures, presented at the 2nd International Conference on Biomedical Ontology (ICBO) 2011