Craton margins can be subject to a wide array of gold genesis and redistribution processes, although high-grade terrains on craton margins are frequently viewed as less prospective than lower-grade counterparts. In contrast to this, the high-grade Tropicana Zone, a newly defined Archean crustal component on the eastern margin of the Yilgarn Craton within the Albany–Fraser Orogen (AFO), contains a significant Proterozoic gold deposit. This deposit and zone comprise mid-amphibolite to granulite-facies gneissic rocks with evidence of partial melting and granite injection. The Tropicana Zone contains significant low-Si, LILE-enriched, granites classed as sanukitoids. Along with the distinctive compositions, the rarity of these rocks within any Archean craton suggests that the granitoid protoliths represent a single suite, emplaced during one event.