— In this technology-driven age, meaningful teaching and learning cannot take place where old tools are applied. Scientific tools are regularly being updated and new ones introduced in teaching and learning across board. With the current advancement in modeling and simulation tools, many virtual analyses in science can be done quickly and effectively than was the case many years back. Taking full advantage of these tools will offer better learning and impartation of basic scientific principles. This paper highlights the need for regular enhancement of scientific curriculum for human capacity development to meet scientific literacy in Africa. Stake holders identified capable of making inputs into curriculum enhancement are employers, educators and the state. A procedure for broad based curriculum assessment and correlation among institutions for effective monitoring and standardization was also presented in this paper using a simulated study of Mechanical Engineering curricula of six virtual universities based on contact hours, units and integration of scientific packages in teaching modules. The results of the simulated study were presented on radar, doughnut, column and pie charts to reveal the variations in contact hours per program which could easily be used by standardization agencies across board all curricula. Regular curriculum review, effective curricular enhancement, clear course goal and objectives, capacity development of academic and technical staff were adjudged to contribute to improved literacy and meeting international practices.