Dissemin is shutting down on January 1st, 2025

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Elsevier, Clinical Microbiology and Infection, (12), p. 3-7, 2006

DOI: 10.1111/j.1469-0691.2006.01656.x

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Rapid streptococcal testing for sore throat and antibiotic resistance

Journal article published in 2006 by R. D. Sheeler, P. Little ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

This article briefly summarises the arguments for and against the routine use of rapid antigen testing for group A β-haemolytic streptococcal pharyngitis and the deficiencies in the current evidence base in this area. Currently, most commercial tests are immunoassays with a sensitivity of 70–95% (average 85%) and a specificity of 95–99%, depending on the comparator and patient population. Rapid antigen testing is recommended and commonly used in the USA, especially for patients in whom group A β-haemolytic streptococcal infection is clinically likely or who have any symptoms plus direct contact exposure. However, there is no consensus in Europe regarding the role of rapid testing. There remains a need for randomised trials to evaluate its benefit to patients and its cost-effectiveness compared with the main alternatives, including delayed antibiotic prescribing.