Because of high costs and time consuming common HIV tests, new ways in diagnosis, offering rapid, cheap, and accuracy possibility are looking for. One of the most promising fields is electrochemistry, providing very good specifity, relatively low price, sensitivity, and possibility of miniaturization. Good sensitivity of electrochemical methods also facilitates the detection of HIV virions during the diagnostic window, i.e. the period when HIV antibodies are produced, but under detection limits of common diagnostic methods. In this review, the advantages of electrochemical HIV biosensor are summarized. Moreover, the potential of electrochemistry compared with other conventional methods is discussed.