Published in
Public Library of Science, PLoS ONE, 9(7), p. e44623, 2012
DOI: 10.1371/journal.pone.0044623
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- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Connection between Genetic and Clinical Data in Bipolar Disorder
Journal article published in 2012 by
Erling Mellerup,
Ole Andreassen 
,
Bente Bennike,
Henrik Dam,
Srdjan Durovic,
Thomas Hansen ,
Ingrid Melle,
Gert Lykke Møller,
Ole Mors,
Pernille Koefoed
,
Bente Bennike,
Henrik Dam,
Srdjan Durovic,
Thomas Hansen ,
Ingrid Melle,
Gert Lykke Møller,
Ole Mors,
Pernille Koefoed
This paper is made freely available by the publisher.
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Abstract
Complex diseases may be associated with combinations of changes in DNA, where the single change has little impact alone. In a previous study of patients with bipolar disorder and controls combinations of SNP genotypes were analyzed, and four large clusters of combinations were found to be significantly associated with bipolar disorder. It has now been found that these clusters may be connected to clinical data.