In spite of the high air quality and health relevance of PM emissions from road dust resuspension in large cities, very little is known on their temporal variability, severely hampering a reliable description of population exposure by dispersion models. We have experimentally monitored the mobile dust load (only inhalable fraction) in two different European urban environments resulting in the first empirical description of the temporal variation of road dust emission strength. In Central (The Netherlands) and Southern (Spain) European environments the loadings of mobile road dust particles <10 μm were found to be generally constant on a day-to-day scale, except during and in the hours immediately after rain events when the mobility of particles drops dramatically to values close to zero. After the rain event the mobile dust load increases exponentially tending to reach again the maximum value, result of the equilibrium between mobilization/buildup of dust and moistening/resuspension processes. The mobilization/buildup of particles smaller than 10 μm was found to be three times faster in Barcelona than in Utrecht, in relation to higher solar radiation. In Barcelona the recovery of mobile road dust reached 50%, 75%, and 90% of the maximum value after 8, 16 and 27 h, respectively. These values were independent of amounts of rain. In Utrecht the same thresholds were reached after, 28, 55 and 90 h, respectively. Our observations may suggest that, for reducing road dust emissions, light but frequent moistening of roads might be more effective than intensive occasional cleanings.