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Elsevier, Tetrahedron Letters, 26(55), p. 3581-3584, 2014

DOI: 10.1016/j.tetlet.2014.02.025

Wiley-VCH Verlag, ChemInform, 49(45), p. no-no, 2014

DOI: 10.1002/chin.201449166

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Regiospecific strategies for the synthesis of novel dihydropyrimidinones and pyrimidopyridazines catalyzed by molybdate sulfuric acid

Journal article published in 2014 by Bahador Karami, Saeed Khodabakhshi ORCID, Sedigheh Akrami, Mahnaz Farahi
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

The one-pot reactions of aryl glyoxals with acetylacetone and urea using molybdate sulfuric acid (5 mol %) lead to the novel functionalized 5-acetyl-4-(aryloyl)-3,4-dihydropyrimidinones, which readily undergo the Knorr condensation with hydrazines to produce new pyrimido[4,5-d]pyridazines. The present strategies are in accordance with green chemistry principles through the use of a safe and recyclable catalyst under solvent-free conditions.