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Taylor and Francis Group, Transcription, 4(2), p. 173-178, 2011

DOI: 10.4161/trns.2.4.16344

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Modeling of chromosomal epigenetic silencing processes

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Silenced genes in eukaryotes are packaged into heterochromatin. In addition to establishing a passive storage site for inactive genes in differentiated cells, silencing can play an active role in promoting cellular differentiation. Here, we describe quantitative modeling of silencing processes.