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Proceedings of the 4th International Symposium on Applied Sciences in Biomedical and Communication Technologies - ISABEL '11

DOI: 10.1145/2093698.2093832

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Allergy detection with statistical modelling of HRV-based non-reaction baseline features

Journal article published in 2011 by Niall Twomey, Andrey Temko, Jonathan O ' B Hourihane, William P. Marnane
This paper is available in a repository.
This paper is available in a repository.

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Abstract

This paper investigates the automated classification of oral food challenges ('allergy tests'). The electrocardiograms (ECG) of the subjects being tested for allergies were recorded via a wireless mote, and the QRS complexes were manually annotated and 18 features were extracted from the signals. Principal component analysis was used for feature decorelation and dimensionality reduction and diagonal covariance Gaussian mixture models were used to model non-reaction baseline patient condition. The generated subject independent log likelihood plots were used to separate allergic reaction by means of subject adaptive thresholding. The platform resulted in 87% accuracy of classification with 100% specificity. The algorithm presented can detect allergy up to 30 minutes sooner than the current state of the clinical art allergy detection (7minutes ± 9).