Kinetic Differentiation between Homo- and Alternating AT DNA by Sterically Restricted Phosphonium Dyes
Journal article published in 2012 by
Lidija-Marija Tumir,
Ivo Crnolatac,
Todor Deligeorgiev,
Aleksey Vasilev,
Stefka Kaloyanova,
Marina Grabar Branilovic,
Marina Grabar Branilović,
Sanja Tomić,
Ivo Piantanida 
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Abstract
Poly has a tracker: By sterically controlling monomer-dimer equilibria, novel dyes can kinetically differentiate between homo-AT and alternating AT-AT polynucleotides. In this way, the width and steric occupation of the DNA minor groove can be finely probed and can be easily assessed by induced CD signals.