Lippincott, Williams & Wilkins, Survey of Anesthesiology, 5(51), p. 232, 2007
DOI: 10.1097/01.sa.0000267103.16356.6e
Oxford Medicine Online
DOI: 10.1093/med/9780190467654.003.0047
50 Landmark Papers, p. 282-283, 2019
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As part of the Keystone Intensive Care Unit project a bundle of evidence-based interventions was introduced in ICUs across the state of Michigan with the goal of decreasing catheter-related bloodstream infections (CRBI). The bundle included (1) hand washing, (2) full barrier precautions during placement of central venous catheters, (3) skin cleaning with chlorhexidine, (4) if possible, avoidance of femoral site, and (5) removing unnecessary central venous catheters. Post implementation rates of catheter-related bloodstream infections were compared to baseline data. The results showed a decrease from a baseline median rate of 2.7 infections per 1000 catheter-days to a median rate of 0 infections per 1000 catheter-days, which was sustained over 18 months of follow-up.