Published in
Cell Press, Current Biology, 19(19), p. R909-R910, 2009
DOI: 10.1016/j.cub.2009.09.001
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Sex Determination: Two Copies for One Cock
Journal article published in 2009 by
Hans Ellegren
This paper is made freely available by the publisher.
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Abstract
The molecular mechanism of sex determination in birds has long remained mysterious. Genetically male chicken embryos, which have two Z sex chromosomes, develop female gonads when the Z chromosome-linked gene DMRT1 is knocked out. This suggests that sex is determined by Z chromosome dosage.