1961-2003, with considerable spatial, interannual and inter-decadal variability. We present a new analysis of millions of ocean temperature profiles designed to filter out local dynamical changes to give a more consistent view of the underlying warming. Time series of temperature anomaly for all waters warmer than 14C show large reductions in interannual to inter-decadal variability and a more spatially uniform upper ocean warming trend (0.12 Wm2 on average) than previous results. This new measure of ocean warming is also more robust to some sources of error in the ocean observing system. Our new analysis provides a useful addition for evaluation of coupled climate models, to the traditional fixed depth analyses. Citation: Palmer, M. D., K. Haines, S. F. B. Tett, and T. J. Ansell (2007), Isolating the signal of ocean global warming, Geophys. Res. Lett., 34, L23610, doi:10.1029/2007GL031712.