Wiley, Helvetica Chimica Acta, 6(98), p. 834-841, 2015
Wiley-VCH Verlag, ChemInform, 44(46), p. no-no
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Six new casbane diterpenoids, sinularcasbanes G-L (1-6, resp.) were isolated from the soft coral Sinularia sp. Their structures were established by extensive spectroscopic analyses, especially 2D-NMR and HR-ESI-MS. The configuration was confirmed by CD analyses and by comparison with data reported in the literature. The compounds were evaluated for cytotoxicity against ten human cancer cell lines (H1975, U937, K562, BGC823, MOLT-4, MCF-7, A549, HeLa, HL60, and Huh-7) and showed no activity.