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Wiley, Helvetica Chimica Acta, 6(98), p. 834-841, 2015

DOI: 10.1002/hlca.201400341

Wiley-VCH Verlag, ChemInform, 44(46), p. no-no

DOI: 10.1002/chin.201544212

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New Casbane Diterpenoids from the Hainan Soft Coral Sinularia Species

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Six new casbane diterpenoids, sinularcasbanes G-L (1-6, resp.) were isolated from the soft coral Sinularia sp. Their structures were established by extensive spectroscopic analyses, especially 2D-NMR and HR-ESI-MS. The configuration was confirmed by CD analyses and by comparison with data reported in the literature. The compounds were evaluated for cytotoxicity against ten human cancer cell lines (H1975, U937, K562, BGC823, MOLT-4, MCF-7, A549, HeLa, HL60, and Huh-7) and showed no activity.