Published in
American Society for Microbiology, Journal of Clinical Microbiology, 7(47), p. 2355-2357, 2009
DOI: 10.1128/jcm.01320-08
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- [www.ncbi.nlm.nih.gov] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Gamma Interferon Release Assays for Diagnosis of Tuberculosis Infection in Immune-Compromised Children in a Country in Which the Prevalence of Tuberculosis Is Low
Journal article published in 2009 by
E. Bruzzese,
M. Bocchino,
L. R. Assante,
M. Alessio,
B. Bellofiore,
D. Bruzzese 
,
R. Iorio,
A. Matarese,
G. Santoro,
P. Vajro,
A. Guarino,
A. Sanduzzi
,
R. Iorio,
A. Matarese,
G. Santoro,
P. Vajro,
A. Guarino,
A. Sanduzzi
This paper is made freely available by the publisher.
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Abstract
Commercial interferon-gamma release assays (IGRAs), T.SPOT.TB and QuantiFERON TB Gold "In tube", were compared with tuberculin skin test for detection of tuberculosis (TB) infection in immune-compromised children in a low prevalence country. IGRAs are of limited usefulness in this study setting due to high rates of discordant and indeterminate results.